Cholesterol isn’t just about the heart — it also affects the brain.
A new study shows that lower cholesterol levels can be linked to up to an 80% lower risk of dementia.
The researchers analyzed over 1 million people and used genetic variants that mimic the effect of cholesterol-lowering medications (statins, ezetimibe and CETP inhibitors). People who naturally had lower LDL also had a dramatically lower risk of dementia.
The same pattern was seen in those who lower their cholesterol with medication:
- 76% lower risk via statin-like mechanisms
- 82% lower risk via ezetimibe
- 70% lower risk via CETP inhibitors
The explanation? High cholesterol can harm the brain by contributing to atherosclerosis, impaired blood circulation and inflammation — processes that drive cognitive decline. What protects the heart likely also protects the brain.
The study does not prove that statins directly prevent dementia, but it underlines the importance of healthy cholesterol levels throughout life.
If you haven’t done it recently: have your cholesterol checked. Preferably already in your 30s–40s.
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