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Cholesterol and Dementia: What’s Good for the Heart Is Good for the Brain

High LDL raises dementia risk, while lowering cholesterol supports both heart and brain health—research shows it doesn’t harm memory or cognition.

Maintaining optimal cholesterol levels is not only important for cardiovascular health – it can also significantly reduce the risk of dementia. A large-scale study published in Journal of Neurology, Neurosurgery & Psychiatry analysed data from over 570,000 adults in South Korea. The results were striking: individuals with LDL-cholesterol levels under 70 mg/dl had a
• 26 % lower risk of developing dementia from any cause
• 28 % lower risk of developing Alzheimer’s disease

In addition, the study found that among individuals with low LDL-cholesterol levels, the use of statins was associated with an additional 13 % reduction in dementia risk.
The experts suggest that elevated LDL-C may contribute to inflammation and oxidative stress, both of which are involved in cognitive decline and neurodegeneration.

Practical conclusion:
Incorporating heart-healthy habits — such as a balanced diet rich in fruits, vegetables, whole grains and healthy fats — together with regular physical activity supports both cardiovascular and cognitive longevity. If you aim to reduce your risk of dementia, it’s time to review your lipid profile.

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